1-Panel Urine Test:
BAR

Item: DBA-114

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Panel Target Compound Cutoff Level
BAR Secobarbital 300 ng/mL
BAR Panel: Specifications

Summary - BAR Drug Test Panel

  • Barbiturates are a class of CNS depressant drugs that possess similar chemistry and mechanism of action. These actions produce varying levels of relaxation, euphoria, drowsiness, and/or unconsciousness, depending on the specific drug and dose. As a result, barbiturates are indicated for a number of medical purposes: as sedatives, as hypnotics for treating insomnia, as anticonvulsants, and as preanesthetics to reduce anxiety prior to surgery. The sedative properties of barbiturates make them attractive to recreational users, while the hypnotic properties make them prone to illicit use by individuals that have difficulty sleeping. Barbiturates are often misused in combination with CNS stimulant drugs, such as cocaine, amphetamine, or methamphetamine, either to neutralize the effects of the stimulant drug or to expedite sleep. [1]

  • Barbiturates are highly addictive and prone to a high degree of physical dependence. For the barbiturate addicted attempting abstinence, withdrawal symptoms can be debilitating and long lasting, often requiring professional assistance. Tolerance to barbiturates occurs quickly and physical dependence poses a threat, so medical treatments are typically limited to the short-term. With higher doses, death by overdose is a strong concern. Consequently, barbiturates are prominent in cases of physician-assisted suicide. [2] Barbiturates were commonly prescribed until the 1970s, when for the most part, they were replaced by the relatively safer benzodiazepines. [1] Typically, barbiturates are reserved for situations where benzodiazepines or other alternatives are ineffective. [3]

  • Secobarbital is the target compound for the BAR One Step Barbiturates Drug Test, detected at a cutoff level of 300 ng/mL. Secobarbital is prescribed under the brand name Seconal, in oral capsule form, indicated as a hypnotic for the short-term treatment of insomnia and as a preanesthetic. [4] In years past, Seconal was commonly misused as a recreational drug and was known by the slang name reds. Approximately 5% of a secobarbital dose of is excreted in the urine as unchanged secobarbital. [5]

  • Phenobarbital cross-reacts with this test at 100 ng/mL. Phenobarbital is dispensed under the brand name Luminal, with many generic labels, in tablet, liquid elixir, and injectable forms. Phenobarbital tablet is indicated as a sedative and as an anticonvulsant. [6] Phenobarbital elixir is indicated as a sedative and as an anticonvulsant for the treatment of seizures. [7] Phenobarbital sodium injection is indicated as a sedative, as a hypnotic for the short-term treatment of insomnia, as a preanesthetic, and as a long-term anticonvulsant. [8] Approximately 10–21% of a phenobarbital dose of is excreted in the urine as unchanged phenobarbital. [9]

Specificity - BAR Drug Test Panel

The following compounds are detected positive in urine by the BAR One Step Barbiturates Drug Test at 5 minutes. Cutoff represents the concentration of each compound required to yield a positive reading, expressed in nanograms of compound per milliliter of urine (ng/mL). A lower cutoff indicates a greater ability to detect the compound.

Compound Synonyms / Brand Names / Common Names Cutoff
(ng/mL)
Secobarbital Quinalbarbitone, Secobarbitone / Seconal / Reds 300
Alphenal Phenallymal, Fenallymal 150
Amobarbital Amylobarbital, Amylobarbitone / Amytal 300
Aprobarbital Aprobarbitone 200
Butabarbital Butabarbitone, Secbutabarbital, Secbutobarbitone / Butisol 75
Butalbital Allzital, Butapap, Fioricet, Fiorinal, Lanorinal 2,500
Butethal Butobarbital, Butobarbitone 100
Cyclopentobarbital Cyclopentobarbitone 600
Pentobarbital Pentobarbitone / Nembutal 300
Phenobarbital Phenobarbitol, Phenobarbitone, Fenobarbital / Luminal 100