1-Panel Urine Test:
AMP

Item: DAM-114

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Panel Target Compound Cutoff Level
AMP d-Amphetamine 1,000 ng/mL
AMP Panel: Specifications

Summary - AMP Drug Test Panel

  • Amphetamine is a CNS stimulant drug, prescribed for treating ADHD, narcolepsy, and obesity, typically found in oral capsule or tablet form. Due to its potent stimulant effects, amphetamine is a popular target for illicit use by students, athletes, recreational users, and those seeking to avoid sleep for various reasons. Such users typically procure the drug, directly or indirectly, from individuals possessing legitimate prescriptions. Amphetamine carries a high potential for addiction and misuse. In attempt to maximize its effects or speed of onset, some amphetamine users will crush the tablets into a powder form and consume the product by snorting, smoking, or injecting after liquefying. [1]

  • Amphetamine's three most notable forms are d-amphetamine, l-amphetamine, and dl-amphetamine. The d- (dextro) and dl- (racemic) forms exhibit stronger CNS effects than the l- (levo) form and are the forms primarily used by pharmaceutical manufacturers. dl-Amphetamine (racemic amphetamine) is a combination of d-amphetamine and l-amphetamine. In medical or scientific publications, in addition to medication labeling, dl-amphetamine is frequently referred to simply as amphetamine. Illicit street amphetamine is typically dl-amphetamine in the form of a white to yellow powder. [2] Speed is a slang name commonly used in years past for various forms of amphetamine.

  • d-Amphetamine is the target compound for the AMP One Step Amphetamine Drug Test, detected at a cutoff level of 1,000 ng/mL. d-Amphetamine is indicated for the treatment of ADHD and narcolepsy: in oral capsule form under generic labels and the brand Dexedrine; in oral tablet form under generic labels; and in oral solution form under generic labels. [3] Approximately 27–53% of a d-amphetamine dose is excreted in the urine as unchanged d-amphetamine. Urine pH has a significant impact on these rates, with higher values in acidic (lower pH) urine and lower values in alkaline (higher pH) urine. [4]

  • The Adderall brand is a combination of d-amphetamine and dl-amphetamine, known as mixed amphetamine salts. Adderall, its generic equivalents, and the new brand Mydayis, are found in oral capsule form, indicated for treating ADHD only; [5] while oral tablet forms of mixed amphetamine salts are indicated for treating ADHD in addition to narcolepsy. [6] Adderall misuse is common in college settings, used as a study aid and for general recreational purposes. Adderall might also be found in amateur or professional athletic circles, where amphetamines are classified as banned performance-enhancing drugs (PEDs) when used outside of a valid medical context. [7]

  • Newer ADHD drugs based on dl-amphetamine are available and prescribed: in oral tablet form under the brand Adzenys, and in oral suspension form under the brands Adzenys and Dyanavel. In addition to ADHD, the Evekeo brand of oral tablets is also indicated for treating narcolepsy and obesity. [8]

  • MDA cross-reacts cross-reacts with this test at 2,000 ng/mL. MDA is one form of the designer drug ecstasy and is a minor urinary metabolite of MDMA, which is also a form of ecstasy. [9] It should be noted, however, that detection of ecstasy use is outside the scope of an amphetamine test device. Instead, an ecstasy test device should be employed, such as the MDMA One Step Ecstasy Drug Test, which detects the three forms of ecstasy: MDMA, MDA, and MDEA.

  • Phentermine cross-reacts with this test at 3,000 ng/mL. Phentermine is a prescription obesity drug, dispensed under the brand names Adipex, Lomaira, and Qsymia, in addition to generic versions. It should be noted, however, that detection of phentermine use is outside the scope of an amphetamine test device.

  • The CNS stimulant drug methamphetamine is known to be metabolized and excreted in the urine as both methamphetamine and amphetamine. In normal urine (pH 6–8), 37–54% of a d-methamphetamine dose is excreted as unchanged d-methamphetamine, with 4–7% as d-amphetamine. [10] It should be noted, however, that detection of methamphetamine use is outside the scope of an amphetamine test device. Instead, a methamphetamine test device should be employed, such as the mAMP One Step Methamphetamine Drug Test, which targets d-methamphetamine at 1,000 ng/mL.

Specificity - AMP Drug Test Panel

The following compounds are detected positive in urine by the AMP One Step Amphetamine Drug Test at 5 minutes. Cutoff represents the concentration of each compound required to yield a positive reading, expressed in nanograms of compound per milliliter of urine (ng/mL). A lower cutoff indicates a greater ability to detect the compound.

Compound Synonyms / Brand Names / Common Names Cutoff
(ng/mL)
d-Amphetamine Dextroamphetamine, Dexamphetamine, Dexamfetamine / Dexedrine, Adderall, Mydayis / Speed 1,000
dl-Amphetamine Amphetamine, Racemic amphetamine, Desoxynorephedrine, Amphetamin, Amfetamine, Amfetamin, Amfetamina, Anfetamina / Adzenys, Dyanavel, Evekeo, Adderall, Mydayis / Speed 3,000
l-Amphetamine Levoamphetamine, Levamphetamine, Levamfetamine, Levamfetamin, Levanfetamina 50,000
3,4-Methylenedioxy-amphetamine MDA, Tenamfetamine, Tenamfetamina / Ecstasy, Molly 2,000
Phentermine Phentermin, Fentermina / Adipex, Lomaira, Qsymia 3,000