• Opioid Use Disorder (OUD):
    A problematic pattern of opioid use leading to clinically significant impairment or distress. Symptoms of OUD include: strong desire for opioids; inability to control or reduce use; continued use despite interference with major obligations or social functioning; use of larger amounts over time; development of tolerance; spending a great deal of time to obtain and use opioids; and withdrawal symptoms that occur after stopping or reducing use, such as flu-like symptoms, exhaustion, fatigue, depression, anxiety, cramps, muscle aches, fever, chills, perspiration, diarrhea, nausea, and vomiting.